[Update August 3, 2013: The site is back online and the bug noted below (which I still believe is a feature) has been fixed.  Selecting San Francisco as a target no longer targets New York City.]

NukeMap3D shows you the future that we at pfpfp hope for. Pick your target city, …

 … or you can just type in a city name.  I picked Downer’s Grove, Illinois, southwest of Chicago:

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If you want to play with my setup (target: Downer’s Grove, IL; 1 megaton blast) click here.  If you’d just like to see a video, here it is:

Alex has been kind enough to estimate of casualties as well as a map of the likely spread of fallout:

NukeMap3D: at pfpfp.org we fully support this effort.